The Substance

Release	September 20, 2024 (Limited)
Cast	Demi Moore, Margaret Qualley, Dennis Quaid
Director	Coralie Fargeat
Writer	Coralie Fargeat
Genres	Drama, Horror
Studio	MUBI
Length	140 mins.
Website	trythesubstance.com

Synopsis

Elisabeth Sparkle (Demi Moore), a former A-lister past her prime, is suddenly fired from her fitness TV show by repellent studio head Harvey (Dennis Quaid).

She is then drawn to the opportunity presented by a mysterious new drug: THE SUBSTANCE. All it takes is one injection and she is reborn – temporarily – as the gorgeous, twenty-something Sue (Margaret Qualley).

The only rule? Time needs to be split: exactly one week in one body, then one week in the other. No exceptions. A perfect balance. What could go wrong?

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